The IQVIA Core Obesity and Diabetes Model (CODM) is a single, integrated, treatment‑agnostic disease model that simulates long‑term clinical and economic outcomes for cardiometabolic conditions, including obesity. Built on the widely accepted Core Diabetes Model, CODM captures 10+ cardiometabolic conditions by jointly modeling evolving risk factors, disease trajectories, treatment use, and the long‑term progression of clinical outcomes and costs, to support robust HTA, payer, policy, and population‑health decision‑making in a rapidly evolving cardiometabolic landscape.