Obesity clinical trials face significant challenges, including recruiting and retaining qualified participants amid increasing competition and complex eligibility criteria. Patients often experience emotional and psychological burdens, stigma, and barriers to care, which can lead to high dropout rates. Ensuring representation, providing personalized support such as nutritional counseling and digital engagement tools, and managing site workload are ongoing concerns for sponsors and research teams. Additionally, adapting strategies to different regions and meeting evolving regulatory requirements add further complexity. Unlock practical strategies to overcome the toughest challenges in obesity clinical trials—read the whitepaper now to discover actionable solutions for patient recruitment, retention, diversity, and operational success.