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Beyond the Protocol - How can sites be empowered for optimum trial performance
Sep 26, 2025
Beyond the Protocol: Empowering Sponsors, Sites, and Patients
Clinical trial performance improves when site enablement goes beyond protocol adherence. Rising complexity—stringent eligibility criteria, competing studies, and extended follow‑up—slows recruitment and strains retention. Sponsors and CROs can relieve operational burden by simplifying designs and equipping sites with tools and workflows that focus effort where it matters: enrolling and retaining the right patients while protecting data integrity.
Reduce Site Burden to Improve Recruitment and Retention
Eligibility rules, prior medication requirements, and overlapping studies make patient identification time‑consuming. Streamlined procedures and clear decision support free site staff to engage eligible participants and sustain adherence throughout longer endpoints—directly improving the patient experience with fewer delays and clearer expectations.
Broad reminders create noise. A risk‑based model targets messages to each site's current performance and study needs, guided by a comprehensive plan set at startup and adapted as the environment changes. Focused, timely outreach helps sites prioritize actions, accelerating study milestones and reducing patient wait times.
High‑Touch Enablement: CRAs + Clinical Trial Educators
CRAs ensure compliance and training. Clinical Trial Educators (CTEs) add personalized guidance on protocol intent and system workflows, reducing deviations and enhancing confidence. The combined model delivers a concierge‑level site experience that supports faster activation and more consistent visit execution—benefits patients feel as simpler journeys and fewer disruptions.
Evolve Site Models for Sustainable Performance
Diversified roles, supportive technology, and options such as remote or in‑home activities allow sites to expand capacity without additional burden, improving access and continuity for patients.
Partner with IQVIA: We design and operationalize risk‑based communications, CTE programs, and site‑centric models tailored to your portfolio. Contact IQVIA to discuss custom solutions that advance sponsor goals, site performance, and patient outcomes.