Planning clinical trials can be full of obstacles, the biggest of which is often picking sites that can recruit the most patients. Adding sites or tweaking inclusions can increase enrollment. Yet, budgets can take a hit and timelines can suffer — perhaps even giving competitors a better shot at the market. The right feasibility information can improve the predictability of clinical trials. Given patient-centricity trends, sites are sometimes overlooked in the planning phase but offer many insights. Their input is important as it can enhance protocol design, study setup, patient recruitment and data quality. Balancing feasibility engagement with patient-focused interests can find and enroll the right patients on time and on budget.