Scientific Poster
ISPOR EU Poster: Evaluating Migration Errors in COA Development and Validation of the IQVIA Migration Error Severity Scale (I-MESS)
Dec 17, 2025
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This scientific poster presented at the 2025 ISPOR EU annual conference examines the challenges of migrating clinical outcome assessments (COAs) from paper to electronic formats (eCOA) in clinical trials. It highlights how errors can arise due to operational pressures and technical complexities. The team developed and validated the IQVIA Migration Error Severity Scale (I-MESS), a tool that systematically identifies and rates migration errors by severity, enabling organizations to prioritize corrections and improve data quality. Analysis across eight studies revealed that migration errors are widespread and vary in severity, underscoring the need for routine, scientific evaluation—especially as new technologies like AI are integrated into migration processes to further enhance quality and reliability.

Listen now to Lindsay Hughes as she provides an overview of the poster and key takeaways.

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