Understand the Drivers of Drug Expenditure in the U.S.
Institute Report
Sep 12, 2017

This report provides analysis around a key aspect of medicine spending growth trends: manufacturer net revenues. It draws on previously published analysis in our reports Medicines Use and Spending in the U.S.: A Review of 2016 and Outlook to 2021 (April 2017) and Outlook for Global Medicines Through 2021: Balancing Cost and Value (Dec 2017).

Recent reports of increases in drug list prices and overall spend on medicines have put the spotlight on the cost of medicines in the U.S. The increasing list prices of specific medicines has, in particular, generated significant media attention. These messages have amplified concerns of policy makers, insurers, pharmacy benefit managers and other healthcare stakeholders that drug prices are to blame for rising costs in the U.S. healthcare system.

However, much of the coverage on list prices has left out the more complex context of the prices, including


  • prices actually received by manufacturers or paid by intermediaries or patients
  • the volume usage of the drugs in question
  • the longer term context of the changes in a drug’s prices over time—including periods of price drops after patent protection

In this report you will find an in-depth analysis of the trends in medicine spending growth and manufacturer net revenues suggesting a far more complex situation than one of prices set by manufacturers simply being too high or growing too fast.

In particular the report highlights the dynamics between prices and volume and introduces a novel way of combining market segments to consider the impact of patent expiry alongside other price related elements. The result is a clearer reflection of trends that affect the costs of medicines in the market. The report also notes that the trend of manufacturer revenues and patient costs are evolving in opposing directions, and that patient exposure to cost trends are not uniformly distributed across patients.

You may also be interested in
Contact Us
Contact Us
Contact Us

Email Us

Get in touch today to discover the right solutions for you.

Call Us

We are pleased to speak with you during our standard business hours.

U.S. Toll-Free only
+1 866 267 4479

For international call please find a number in our toll-free list.

IQVIA Institute Inquiries

We are ready to help you better understand and benefit from the work of the IQVIA Institute for Human Data Science. Please get in touch today to learn more.