SOLUTIONS
-
Research & Development
-
Real World Evidence
-
Commercialization
-
Safety & Regulatory Compliance
-
Technologies
LIFE SCIENCE SEGMENTS
HEALTHCARE SEGMENTS
- Information Partner Services
- Financial Institutions
- Global Health
- Government
- Patient Associations
- Payers
- Providers
THERAPEUTIC AREAS
- Cardiovascular
- Cell and Gene Therapy
- Central Nervous System
- GI & Hepatology
- Infectious Diseases & Vaccines
- Oncology & Hematology
- Pediatrics
- Rare Diseases
- View All
Obesity
"Advancing obesity and obesity-related trials with patients at the center of development.
LEARN MORE
Harness the power to transform clinical development
Reimagine clinical development by intelligently connecting data, technology, and analytics to optimize your trials. The result? Faster decision making and reduced risk so you can deliver life-changing therapies faster.
Research & Development OverviewResearch & Development Quick Links
Real World Evidence. Real Confidence. Real Results.
Generate and disseminate evidence that answers crucial clinical, regulatory and commercial questions, enabling you to drive smarter decisions and meet your stakeholder needs with confidence.
REAL WORLD EVIDENCE OVERVIEWReal World Evidence Quick Links
See markets more clearly. Opportunities more often.
Elevate commercial models with precision and speed using AI-driven analytics and technology that illuminate hidden insights in data.
COMMERCIALIZATION OVERVIEWCommercialization Quick Links
Service driven. Tech-enabled. Integrated compliance.
Orchestrate your success across the complete compliance lifecycle with best-in-class services and solutions for safety, regulatory, quality and medical information.
COMPLIANCE OVERVIEWSafety & Regulatory Compliance Quick Links
Intelligence that transforms life sciences end-to-end.
When your destination is a healthier world, making intelligent connections between data, technology, and services is your roadmap.
TECHNOLOGIES OVERVIEWTechnology Quick Links
CLINICAL PRODUCTS
COMMERCIAL PRODUCTS
COMPLIANCE, SAFETY, REG PRODUCTS
REAL WORLD PRODUCTS
- Real World & Healthcare Data
- Health Data Apps & AI
- Analytics Research Accelerator
- Expert Ecosystem
- AI Patient & HCP Profiling- Commercial
- AI Patient & Provider Profiling- Med Affairs
- AI Patient & HCP Profiling- Healthcare
- Natural Language Processing
- Market Access Insights
- Direct-to-Patient Research
BLOGS, WHITE PAPERS & CASE STUDIES
Explore our library of insights, thought leadership, and the latest topics & trends in healthcare.
DISCOVER INSIGHTSTHE IQVIA INSTITUTE
An in-depth exploration of the global healthcare ecosystem with timely research, insightful analysis, and scientific expertise.
SEE LATEST REPORTS
FEATURED INNOVATIONS
-
IQVIA Connected Intelligence™
-
IQVIA AI
-
IQVIA AI Assistant
-
Human Data Science Cloud
-
IQVIA Innovation Hub
-
Decentralized Trials
-
Patient Experience Solutions
WHO WE ARE
- Our Story
- Our Impact
- Commitment to Global Health
- Code of Conduct
- Sustainability
- Privacy
- Executive Team
NEWS & RESOURCES
Unlock your potential to drive healthcare forward
By making intelligent connections between your needs, our capabilities, and the healthcare ecosystem, we can help you be more agile, accelerate results, and improve patient outcomes.
LEARN MORE
IQVIA AI is Healthcare-grade AI®
Building on a rich history of developing AI for healthcare, IQVIA AI connects the right data, technology, and expertise to address the unique needs of healthcare. It's what we call Healthcare-grade AI.
LEARN MORE
Meet the IQVIA AI Assistant
Your new expert analyst is here. Be at the forefront of data-driven decision-making with a new generative AI tool that enables you to interact with our products and solutions like never before. Get results you can trust, faster.
LEARN MORE
Your healthcare data deserves more than just a cloud.
The IQVIA Human Data Science Cloud is our unique capability designed to enable healthcare-grade analytics, tools, and data management solutions to deliver fit-for-purpose global data at scale.
LEARN MORE
Innovations make an impact when bold ideas meet powerful partnerships
The IQVIA Innovation Hub connects start-ups with the extensive IQVIA network of assets, resources, clients, and partners. Together, we can help lead the future of healthcare with the extensive IQVIA network of assets, resources, clients, and partners.
LEARN MORE
Proven, faster DCT solutions
IQVIA Decentralized Trials deliver purpose-built clinical services and technologies that engage the right patients wherever they are. Our hybrid and fully virtual solutions have been used more than any others.
LEARN MORE
IQVIA Patient Experience Solutions
Empowering patients to personalize their healthcare and connecting them to caregivers has the potential to change the care delivery paradigm.
LEARN MOREIQVIA Careers
Featured Careers
Stay Connected
WE'RE HIRING
"At IQVIA your potential has no limits. We thrive on bold ideas and fearless innovation. Join us in reimagining what’s possible.
VIEW ROLESBlog
Beware the Octo-trial
Oct 10, 2017
Immunotherapy has played an integral role in oncology research for more than a century, but in the last few years we’ve seen extraordinary discoveries that are transforming the way we think about cancer treatment. New advances in immunotherapies including cancer vaccines, CAR T-Cell Therapies, PD-1/PD-L1 inhibitors, and other therapies and diagnostics are transforming the standard of care and significantly improving survival rates for these patients.
This transformation is exciting for industry, but it is adding a lot of complexity to the drug development process that sponsors, CROs and investigative sites need to address. Delivering targeted immunotherapies to market requires more sophisticated site selection, and monitoring and oversight processes particularly in early phase trials in which changing standards of care and multiple arms can easily overwhelm site staff adding time, cost and risk to the trial process.
But it doesn’t have to be overwhelming. When sponsors and CROs address the following five challenges they can mitigate many of the risks that come with these trials and increase the ease with which they bring these treatments to market.
Challenge #1: The rapidly changing standard of care
Immuno-oncology research is a constantly changing science, and every new discovery has the potential to impact related ongoing trials. For example, FDA’s approval of nivolumab and pembrolizumab, which are both PD-1 inhibitors, changed the standard of care for non-small cell lung cancer (NSCLC). If a sponsor was running a third-line study after those drugs were approved, the trial might suddenly become difficult to recruit.
To increase site’s adaptability, studies should be designed for flexibility to better enable changes midstream. This includes having pre-defined processes in place to quickly amend protocols, communicate changes to site teams, and reallocate human and capital resources as necessary. It also requires a robust education program for site monitors and investigators to keep them fully up to date on changing safety signals, including evolving toxicity management guidelines, and the importance of tracking immuno-related events as evidence of progression.