As clinical trials become increasingly decentralized and digitally enabled, sponsors must navigate evolving requirements for electronic consent and electronic signatures. This Q&A with IQVIA experts explores the differences between Simple Electronic Signatures (SES), Advanced Electronic Signatures (AES), and Qualified Electronic Signatures (QES), including regulatory considerations, participant identity verification, data privacy, operational impacts, and best practices for global trial implementation. Learn how eConsent solutions can improve participant understanding, support compliance, streamline consent workflows, and enhance audit readiness across multi-regional studies.