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Harness the power to transform clinical development

Reimagine clinical development by intelligently connecting data, technology, and analytics to optimize your trials. The result? Faster decision making and reduced risk so you can deliver life-changing therapies faster.

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Generate and disseminate evidence that answers crucial clinical, regulatory and commercial questions, enabling you to drive smarter decisions and meet your stakeholder needs with confidence.

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Elevate commercial models with precision and speed using AI-driven analytics and technology that illuminate hidden insights in data.

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Orchestrate your success across the complete compliance lifecycle with best-in-class services and solutions for safety, regulatory, quality and medical information.

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When your destination is a healthier world, making intelligent connections between data, technology, and services is your roadmap.

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THE IQVIA INSTITUTE

An in-depth exploration of the global healthcare ecosystem with timely research, insightful analysis, and scientific expertise.

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INSTITUTE REPORT

"Global Trends in R&D 2024

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"DCTs Deliver Big ROI

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"Capturing value at scale: The $4 billion RWE imperative

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Building on a rich history of developing AI for healthcare, IQVIA AI connects the right data, technology, and expertise to address the unique needs of healthcare. It's what we call Healthcare-grade AI.

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The IQVIA Human Data Science Cloud is our unique capability designed to enable healthcare-grade analytics, tools, and data management solutions to deliver fit-for-purpose global data at scale.

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The IQVIA Innovation Hub connects start-ups with the extensive IQVIA network of assets, resources, clients, and partners. Together, we can help lead the future of healthcare with the extensive IQVIA network of assets, resources, clients, and partners.

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IQVIA Decentralized Trials deliver purpose-built clinical services and technologies that engage the right patients wherever they are. Our hybrid and fully virtual solutions have been used more than any others.

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Empowering patients to personalize their healthcare and connecting them to caregivers has the potential to change the care delivery paradigm. IQVIA and Apple are collaborating to bring this exciting future of personalized care directly to devices patients already have and use.

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White Paper
Deal Trends in Gene Therapy
IQVIA Pharma Deals
Dec 04, 2019
  • Library
  • Deal Trends in Gene Therapy
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This White Paper, by IQVIA Pharma Deals, provides an insightful overview of deal activity in the gene therapy market covering both in vivo and ex vivo approaches.

Gene therapies hold significant promise as a long-lasting, if not permanent, treatment for patients with life-changing disorders such as amyotrophic lateral sclerosis, Parkinson’s disease and certain types of cancers. The concept of gene therapy, which has been around since the 1970s, involves the introduction of normal genes into cells in place of missing or defective ones to correct genetic disorders. After the first clinical success in 1990 in which a patient with severe combined immunodeficiency was delivered a functional copy of the adenosine deaminase gene, the field began to gain momentum and garner significant interest from investors and the pharmaceutical industry. However, the initial enthusiasm was stalled by the death of a healthy volunteer during a clinical trial testing the safety of a treatment for ornithine transcarbamylase (OTC) deficiency in 1999. The patient suffered an immune response triggered by the viral vector used to carry the corrective OTC gene leading to multiple organ failure and brain death. More recently, the field has recovered with the US FDA citing more than 500 active IND applications involving gene therapy products in 2018, reflecting the intensity of interest in this field1. Gene therapies discussed in this White Paper include both in vivo and ex vivo approaches, which refer to the genetic modification of a patient’s cells inside and outside the body (before being returned to the patient), respectively.


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Cell & Gene Therapy

Access new resources for advanced therapy development, from candidate identification through market authorization.

Clinical Trials

Change the model of clinical research by integrating data, expertise, analytics and technology from study design through execution to power better decisions.

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